Schedule:
Please note: All rankings shown are the rankings of the teams on the date that they played one another
| Game | Date | Away Team (Rank) | Away Score | Home Score | Home Team (Rank) | Game Status | Result | Margin |
|---|---|---|---|---|---|---|---|---|
| 1 | 2025-11-03 | Colgate (266) | 69 | 80 | Michigan State (7) | Final | W | 11 |
| 2 | 2025-11-08 | Arkansas (31) | 66 | 69 | Michigan State (7) | Final | W | 3 |
| 3 | 2025-11-13 | San Jose State (177) | 60 | 79 | Michigan State (7) | Final | W | 19 |
| 4 | 2025-11-18 | Michigan State (7) | 83 | 66 | Kentucky (9) | Final | W | 17 |
| 5 | 2025-11-21 | Detroit (328) | 56 | 84 | Michigan State (7) | Final | W | 28 |
| 6 | 2025-11-25 | Michigan State (7) | 89 | 56 | East Carolina (164) | Final | W | 33 |
| 7 | 2025-11-27 | Michigan State (7) | 74 | 58 | North Carolina (40) | Final | W | 16 |
| 8 | 2025-12-02 | Iowa (15) | 52 | 71 | Michigan State (6) | Final | W | 19 |
| 9 | 2025-12-06 | Duke (2) | 66 | 60 | Michigan State (6) | Final | L | -6 |
| 10 | 2025-12-13 | Michigan State (7) | 76 | 72 | Penn State (70) | Final | W | 4 |
| 11 | 2025-12-16 | Toledo (157) | 69 | 92 | Michigan State (9) | Final | W | 23 |
| 12 | 2025-12-20 | Oakland (136) | 70 | 79 | Michigan State (9) | Final | W | 9 |
| 13 | 2025-12-29 | Cornell (185) | 97 | 114 | Michigan State (10) | Final | W | 17 |
| 14 | 2026-01-02 | Michigan State (10) | 56 | 58 | Nebraska (8) | Final | L | -2 |
| 15 | 2026-01-05 | USC (27) | 51 | 80 | Michigan State (11) | Final | W | 29 |
| 16 | 2026-01-08 | Northwestern | Michigan State | Scheduled – 6:30 PM | – | – | ||
| 17 | 2026-01-13 | Indiana | Michigan State | Scheduled – 8:00 PM | – | – | ||
| 18 | 2026-01-16 | Michigan State | Washington | Scheduled – 9:00 PM | – | – | ||
| 19 | 2026-01-20 | Michigan State | Oregon | Scheduled – 6:00 PM | – | – | ||
| 20 | 2026-01-24 | Maryland | Michigan State | Scheduled – 12:00 PM | – | – | ||
| 21 | 2026-01-27 | Michigan State | Rutgers | Scheduled – 6:30 PM | – | – | ||
| 22 | 2026-01-30 | Michigan | Michigan State | Scheduled – 8:00 PM | – | – | ||
| 23 | 2026-02-04 | Michigan State | Minnesota | Scheduled – 6:00 PM | – | – | ||
| 24 | 2026-02-07 | Illinois | Michigan State | Scheduled – 8:00 PM | – | – | ||
| 25 | 2026-02-13 | Michigan State | Wisconsin | Scheduled – 7:00 PM | – | – | ||
| 26 | 2026-02-17 | UCLA | Michigan State | Scheduled – 8:30 PM | – | – | ||
| 27 | 2026-02-22 | Ohio State | Michigan State | Scheduled – 1:00 PM | – | – | ||
| 28 | 2026-02-26 | Michigan State | Purdue | Scheduled – 8:00 PM | – | – | ||
| 29 | 2026-03-01 | Michigan State | Indiana | Scheduled – 3:45 PM | – | – | ||
| 30 | 2026-03-05 | Rutgers | Michigan State | Scheduled – 8:00 PM | – | – | ||
| 31 | 2026-03-08 | Michigan State | Michigan | Scheduled – 5:30 PM | – | – |