Schedule:
Please note: All rankings shown are the rankings of the teams on the date that they played one another
| Game | Date | Away Team (Rank) | Away Score | Home Score | Home Team (Rank) | Game Status | Result | Margin |
|---|---|---|---|---|---|---|---|---|
| 1 | 2018-11-06 | Michigan State (3) | 87 | 92 | Kansas (7) | Final | L | -5 |
| 2 | 2018-11-11 | Florida Gulf Coast (144) | 82 | 106 | Michigan State (3) | Final | W | 24 |
| 3 | 2018-11-14 | Louisiana-Monroe (123) | 59 | 80 | Michigan State (179) | Final | W | 21 |
| 4 | 2018-11-18 | Tennessee Tech (351) | 33 | 101 | Michigan State (179) | Final | W | 68 |
| 5 | 2018-11-22 | Michigan State (58) | 87 | 67 | UCLA (82) | Final | W | 20 |
| 6 | 2018-11-23 | Michigan State (58) | 78 | 68 | Texas (10) | Final | W | 10 |
| 7 | 2018-11-27 | Michigan State (14) | 78 | 82 | Louisville (111) | Final/OT | L | -4 |
| 8 | 2018-11-30 | Michigan State (14) | 78 | 67 | Rutgers (54) | Final | W | 11 |
| 9 | 2018-12-03 | Iowa (11) | 68 | 90 | Michigan State (14) | Final | W | 22 |
| 10 | 2018-12-08 | Michigan State (21) | 63 | 59 | Florida (100) | Final | W | 4 |
| 11 | 2018-12-16 | Green Bay (157) | 83 | 104 | Michigan State (11) | Final | W | 21 |
| 12 | 2018-12-21 | Oakland (258) | 69 | 99 | Michigan State (8) | Final | W | 30 |
| 13 | 2018-12-29 | Northern Illinois (186) | 60 | 88 | Michigan State (13) | Final | W | 28 |
| 14 | 2019-01-02 | Northwestern (63) | 55 | 81 | Michigan State (11) | Final | W | 26 |
| 15 | 2019-01-05 | Michigan State (11) | 86 | 77 | Ohio State (10) | Final | W | 9 |
| 16 | 2019-01-08 | Purdue (32) | 59 | 77 | Michigan State (7) | Final | W | 18 |
| 17 | 2019-01-13 | Michigan State (7) | 71 | 56 | Penn State (98) | Final | W | 15 |
| 18 | 2019-01-17 | Michigan State (8) | 70 | 64 | Nebraska (25) | Final | W | 6 |
| 19 | 2019-01-21 | Maryland (17) | 55 | 69 | Michigan State (8) | Final | W | 14 |
| 20 | 2019-01-24 | Michigan State (5) | 82 | 67 | Iowa (17) | Final | W | 15 |
| 21 | 2019-01-27 | Michigan State (5) | 63 | 73 | Purdue (22) | Final | L | -10 |
| 22 | 2019-02-02 | Indiana (42) | 79 | 75 | Michigan State (6) | Final/OT | L | -4 |
| 23 | 2019-02-05 | Michigan State (7) | 74 | 79 | Illinois (119) | Final | L | -5 |
| 24 | 2019-02-09 | Minnesota (37) | 55 | 79 | Michigan State (7) | Final | W | 24 |
| 25 | 2019-02-12 | Michigan State (9) | 67 | 59 | Wisconsin (19) | Final | W | 8 |
| 26 | 2019-02-17 | Ohio State (32) | 44 | 62 | Michigan State (9) | Final | W | 18 |
| 27 | 2019-02-20 | Rutgers (92) | 60 | 71 | Michigan State (9) | Final | W | 11 |
| 28 | 2019-02-24 | Michigan State (9) | 77 | 70 | Michigan (7) | Final | W | 7 |
| 29 | 2019-03-02 | Michigan State (8) | 62 | 63 | Indiana (59) | Final | L | -1 |
| 30 | 2019-03-05 | Nebraska (52) | 76 | 91 | Michigan State (9) | Final | W | 15 |
| 31 | 2019-03-09 | Michigan (7) | 63 | 75 | Michigan State (9) | Final | W | 12 |
| 32 | 2019-03-15 | Ohio State (47) | 70 | 77 | Michigan State (8) | Final | W | 7 |
| 33 | 2019-03-16 | Wisconsin (16) | 55 | 67 | Michigan State (8) | Final | W | 12 |
| 34 | 2019-03-17 | Michigan (9) | 60 | 65 | Michigan State (8) | Final | W | 5 |
| 35 | 2019-03-21 | Bradley (156) | 65 | 76 | Michigan State (6) | Final | W | 11 |
| 36 | 2019-03-23 | Minnesota (38) | 50 | 70 | Michigan State (6) | Final | W | 20 |
| 37 | 2019-03-29 | LSU (12) | 63 | 80 | Michigan State (6) | Final | W | 17 |
| 38 | 2019-03-31 | Michigan State (6) | 68 | 67 | Duke (2) | Final | W | 1 |
| 39 | 2019-04-06 | Texas Tech (10) | 61 | 51 | Michigan State (6) | Final | L | -10 |