Schedule:
Please note: All rankings shown are the rankings of the teams on the date that they played one another
| Game | Date | Away Team (Rank) | Away Score | Home Score | Home Team (Rank) | Game Status | Result | Margin |
|---|---|---|---|---|---|---|---|---|
| 1 | 2018-11-06 | UMKC (364) | 45 | 76 | Loyola-Chicago (263) | Final | W | 31 |
| 2 | 2018-11-09 | Furman (93) | 60 | 58 | Loyola-Chicago (49) | Final | L | -2 |
| 3 | 2018-11-14 | Niagara (186) | 62 | 75 | Loyola-Chicago (164) | Final | W | 13 |
| 4 | 2018-11-16 | Grambling (160) | 64 | 80 | Loyola-Chicago (164) | Final | W | 16 |
| 5 | 2018-11-19 | Richmond (263) | 66 | 82 | Loyola-Chicago (164) | Final | W | 16 |
| 6 | 2018-11-21 | Loyola-Chicago (85) | 66 | 78 | Boston College (158) | Final | L | -12 |
| 7 | 2018-11-27 | Nevada (9) | 79 | 65 | Loyola-Chicago (112) | Final | L | -14 |
| 8 | 2018-12-01 | Loyola-Chicago (112) | 73 | 64 | Illinois-Chicago (146) | Final | W | 9 |
| 9 | 2018-12-05 | Ball State (103) | 75 | 69 | Loyola-Chicago (106) | Final | L | -6 |
| 10 | 2018-12-08 | Loyola-Chicago (106) | 41 | 55 | Maryland (22) | Final | L | -14 |
| 11 | 2018-12-16 | Norfolk State (276) | 49 | 80 | Loyola-Chicago (126) | Final | W | 31 |
| 12 | 2018-12-18 | Benedictine | 47 | 75 | Loyola-Chicago (118) | Final | W | 28 |
| 13 | 2018-12-22 | Loyola-Chicago (118) | 42 | 45 | Saint Joseph's (146) | Final | L | -3 |
| 14 | 2019-01-02 | Indiana State (111) | 44 | 79 | Loyola-Chicago (143) | Final | W | 35 |
| 15 | 2019-01-05 | Loyola-Chicago (143) | 85 | 74 | Drake (64) | Final | W | 11 |
| 16 | 2019-01-08 | Loyola-Chicago (112) | 48 | 67 | Evansville (197) | Final | L | -19 |
| 17 | 2019-01-12 | Illinois State (179) | 64 | 67 | Loyola-Chicago (112) | Final | W | 3 |
| 18 | 2019-01-15 | Valparaiso (161) | 54 | 71 | Loyola-Chicago (125) | Final | W | 17 |
| 19 | 2019-01-19 | Loyola-Chicago (125) | 75 | 67 | Indiana State (147) | Final | W | 8 |
| 20 | 2019-01-23 | Loyola-Chicago (106) | 35 | 70 | Missouri State (214) | Final | L | -35 |
| 21 | 2019-01-27 | Southern Illinois (162) | 50 | 75 | Loyola-Chicago (106) | Final | W | 25 |
| 22 | 2019-01-30 | Northern Iowa (200) | 60 | 61 | Loyola-Chicago (123) | Final | W | 1 |
| 23 | 2019-02-02 | Loyola-Chicago (123) | 57 | 65 | Illinois State (162) | Final | L | -8 |
| 24 | 2019-02-05 | Drake (100) | 64 | 86 | Loyola-Chicago (134) | Final | W | 22 |
| 25 | 2019-02-10 | Loyola-Chicago (134) | 56 | 51 | Valparaiso (190) | Final | W | 5 |
| 26 | 2019-02-13 | Loyola-Chicago (116) | 54 | 61 | Bradley (191) | Final | L | -7 |
| 27 | 2019-02-17 | Missouri State (173) | 65 | 61 | Loyola-Chicago (116) | Final | L | -4 |
| 28 | 2019-02-20 | Evansville (228) | 58 | 70 | Loyola-Chicago (129) | Final | W | 12 |
| 29 | 2019-02-24 | Loyola-Chicago (129) | 53 | 63 | Southern Illinois (147) | Final | L | -10 |
| 30 | 2019-02-27 | Loyola-Chicago (133) | 56 | 55 | Northern Iowa (172) | Final | W | 1 |
| 31 | 2019-03-02 | Bradley (170) | 68 | 81 | Loyola-Chicago (133) | Final | W | 13 |
| 32 | 2019-03-08 | Valparaiso (204) | 54 | 67 | Loyola-Chicago (127) | Final | W | 13 |
| 33 | 2019-03-09 | Bradley (171) | 53 | 51 | Loyola-Chicago (127) | Final | L | -2 |
| 34 | 2019-03-19 | Loyola-Chicago (129) | 61 | 70 | Creighton (54) | Final | L | -9 |