Schedule:
Please note: All rankings shown are the rankings of the teams on the date that they played one another
| Game | Date | Away Team (Rank) | Away Score | Home Score | Home Team (Rank) | Game Status | Result | Margin |
|---|---|---|---|---|---|---|---|---|
| 1 | 2024-11-04 | North Carolina Wesleyan | 70 | 97 | East Carolina (252) | Final | W | 27 |
| 2 | 2024-11-09 | Coastal Carolina (188) | 59 | 63 | East Carolina (252) | Final | W | 4 |
| 3 | 2024-11-12 | Mount Olive | 73 | 110 | East Carolina (122) | Final | W | 37 |
| 4 | 2024-11-16 | George Mason (169) | 77 | 78 | East Carolina (88) | Final (2OT) | W | 1 |
| 5 | 2024-11-21 | East Carolina (143) | 78 | 86 | Jacksonville State (116) | Final | L | -8 |
| 6 | 2024-11-22 | East Carolina (142) | 71 | 64 | Stetson (356) | Final | W | 7 |
| 7 | 2024-11-23 | East Carolina (252) | 72 | 55 | Illinois-Chicago (139) | Final | W | 17 |
| 8 | 2024-11-29 | North Carolina A&T (265) | 69 | 93 | East Carolina (97) | Final | W | 24 |
| 9 | 2024-12-03 | UNC-Wilmington (102) | 67 | 53 | East Carolina (131) | Final | L | -14 |
| 10 | 2024-12-07 | East Carolina (147) | 68 | 75 | South Carolina (87) | Final | L | -7 |
| 11 | 2024-12-11 | North Alabama (177) | 74 | 67 | East Carolina (172) | Final | L | -7 |
| 12 | 2024-12-17 | Florida International (305) | 64 | 75 | East Carolina (165) | Final | W | 11 |
| 13 | 2024-12-21 | Gardner-Webb (235) | 84 | 79 | East Carolina (180) | Final | L | -5 |
| 14 | 2024-12-31 | East Carolina (196) | 69 | 75 | South Florida (173) | Final | L | -6 |
| 15 | 2025-01-05 | Florida Atlantic (111) | 78 | 76 | East Carolina (202) | Final | L | -2 |
| 16 | 2025-01-08 | Temple (137) | 79 | 80 | East Carolina (183) | Final | W | 1 |
| 17 | 2025-01-11 | East Carolina (184) | 70 | 74 | Memphis (16) | Final | L | -4 |
| 18 | 2025-01-14 | North Texas (79) | 69 | 60 | East Carolina (193) | Final | L | -9 |
| 19 | 2025-01-18 | East Carolina (179) | 75 | 72 | Wichita State (149) | Final | W | 3 |
| 20 | 2025-01-21 | East Carolina (171) | 85 | 76 | Tulsa (300) | Final (OT) | W | 9 |
| 21 | 2025-01-25 | South Florida (203) | 55 | 64 | East Carolina (167) | Final | W | 9 |
| 22 | 2025-02-01 | East Carolina (170) | 94 | 98 | Temple (126) | Final (OT) | L | -4 |
| 23 | 2025-02-05 | Rice (206) | 73 | 60 | East Carolina (188) | Final | L | -13 |
| 24 | 2025-02-08 | East Carolina (176) | 80 | 79 | UTSA (215) | Final | W | 1 |
| 25 | 2025-02-11 | UAB (129) | 75 | 82 | East Carolina (166) | Final | W | 7 |
| 26 | 2025-02-15 | East Carolina (162) | 75 | 59 | Charlotte (262) | Final | W | 16 |
| 27 | 2025-02-19 | East Carolina (165) | 81 | 86 | Tulane (163) | Final | L | -5 |
| 28 | 2025-02-23 | UTSA (243) | 89 | 96 | East Carolina (166) | Final (OT) | W | 7 |
| 29 | 2025-03-02 | Charlotte (260) | 76 | 78 | East Carolina (162) | Final | W | 2 |
| 30 | 2025-03-06 | Tulane (169) | 64 | 73 | East Carolina (157) | Final | W | 9 |
| 31 | 2025-03-09 | East Carolina (161) | 53 | 81 | Florida Atlantic (122) | Final | L | -28 |
| 32 | 2025-03-13 | UTSA (229) | 65 | 70 | East Carolina (163) | Final | W | 5 |
| 33 | 2025-03-14 | East Carolina (157) | 77 | 94 | UAB (116) | Final | L | -17 |