Schedule:
Please note: All rankings shown are the rankings of the teams on the date that they played one another
| Game | Date | Away Team (Rank) | Away Score | Home Score | Home Team (Rank) | Game Status | Result | Margin |
|---|---|---|---|---|---|---|---|---|
| 1 | 2018-11-06 | Delaware State (350) | 56 | 81 | East Carolina (248) | Final | W | 25 |
| 2 | 2018-11-09 | James Madison (254) | 73 | 72 | East Carolina (248) | Final | L | -1 |
| 3 | 2018-11-11 | Lamar (215) | 78 | 84 | East Carolina (248) | Final/OT | W | 6 |
| 4 | 2018-11-16 | East Carolina (144) | 54 | 79 | Georgia Tech (111) | Final | L | -25 |
| 5 | 2018-11-19 | UTRGV (281) | 64 | 69 | East Carolina (144) | Final | W | 5 |
| 6 | 2018-11-21 | Prairie View A&M (294) | 64 | 76 | East Carolina (209) | Final | W | 12 |
| 7 | 2018-11-24 | High Point (281) | 55 | 52 | East Carolina (209) | Final | L | -3 |
| 8 | 2018-11-27 | East Carolina (191) | 86 | 95 | UNC-Wilmington (241) | Final | L | -9 |
| 9 | 2018-11-30 | Appalachian State (265) | 81 | 83 | East Carolina (191) | Final | W | 2 |
| 10 | 2018-12-02 | Maryland-Eastern Shore (333) | 47 | 70 | East Carolina (191) | Final | W | 23 |
| 11 | 2018-12-18 | East Carolina (191) | 49 | 55 | Charlotte (268) | Final | L | -6 |
| 12 | 2018-12-28 | North Carolina A&T (256) | 57 | 77 | East Carolina (216) | Final | W | 20 |
| 13 | 2019-01-02 | East Carolina (203) | 54 | 82 | SMU (132) | Final | L | -28 |
| 14 | 2019-01-05 | Cincinnati (25) | 71 | 73 | East Carolina (203) | Final | W | 2 |
| 15 | 2019-01-10 | East Carolina (192) | 72 | 78 | Memphis (78) | Final | L | -6 |
| 16 | 2019-01-13 | East Carolina (192) | 65 | 76 | Central Florida (31) | Final | L | -11 |
| 17 | 2019-01-16 | Temple (38) | 85 | 74 | East Carolina (197) | Final | L | -11 |
| 18 | 2019-01-23 | East Carolina (199) | 50 | 94 | Houston (8) | Final | L | -44 |
| 19 | 2019-01-26 | South Florida (102) | 77 | 57 | East Carolina (199) | Final | L | -20 |
| 20 | 2019-01-31 | Tulane (291) | 65 | 66 | East Carolina (219) | Final | W | 1 |
| 21 | 2019-02-03 | East Carolina (219) | 52 | 76 | Connecticut (89) | Final | L | -24 |
| 22 | 2019-02-06 | Wichita State (106) | 65 | 49 | East Carolina (214) | Final | L | -16 |
| 23 | 2019-02-10 | East Carolina (214) | 68 | 72 | South Florida (72) | Final/OT | L | -4 |
| 24 | 2019-02-13 | Memphis (69) | 79 | 69 | East Carolina (218) | Final | L | -10 |
| 25 | 2019-02-17 | Tulsa (77) | 77 | 73 | East Carolina (218) | Final/OT | L | -4 |
| 26 | 2019-02-23 | East Carolina (224) | 85 | 81 | Tulane (302) | Final | W | 4 |
| 27 | 2019-02-27 | Houston (4) | 99 | 65 | East Carolina (224) | Final | L | -34 |
| 28 | 2019-03-03 | East Carolina (224) | 78 | 91 | Tulsa (84) | Final | L | -13 |
| 29 | 2019-03-05 | East Carolina (229) | 55 | 72 | Wichita State (88) | Final | L | -17 |
| 30 | 2019-03-10 | Connecticut (104) | 82 | 73 | East Carolina (229) | Final | L | -9 |
| 31 | 2019-03-14 | East Carolina (230) | 57 | 73 | Wichita State (80) | Final | L | -16 |