Schedule:
Please note: All rankings shown are the rankings of the teams on the date that they played one another
| Game | Date | Away Team (Rank) | Away Score | Home Score | Home Team (Rank) | Game Status | Result | Margin |
|---|---|---|---|---|---|---|---|---|
| 1 | 2025-11-04 | Texas (47) | 60 | 75 | Duke (3) | Final | W | 15 |
| 2 | 2025-11-08 | Western Carolina (340) | 54 | 95 | Duke (3) | Final | W | 41 |
| 3 | 2025-11-11 | Duke (3) | 114 | 59 | Army (274) | Final | W | 55 |
| 4 | 2025-11-14 | Indiana State (197) | 62 | 100 | Duke (3) | Final | W | 38 |
| 5 | 2025-11-18 | Kansas (28) | 66 | 78 | Duke (3) | Final | W | 12 |
| 6 | 2025-11-21 | Niagara (320) | 42 | 100 | Duke (3) | Final | W | 58 |
| 7 | 2025-11-23 | Howard (331) | 56 | 93 | Duke (3) | Final | W | 37 |
| 8 | 2025-11-27 | Duke (3) | 80 | 71 | Arkansas (31) | Final | W | 9 |
| 9 | 2025-12-02 | Florida (28) | 66 | 67 | Duke (2) | Final | W | 1 |
| 10 | 2025-12-06 | Duke (2) | 66 | 60 | Michigan State (6) | Final | W | 6 |
| 11 | 2025-12-16 | Lipscomb (119) | 73 | 97 | Duke (2) | Final | W | 24 |
| 12 | 2025-12-20 | Texas Tech (29) | 82 | 81 | Duke (2) | Final | L | -1 |
| 13 | 2025-12-31 | Georgia Tech (137) | 79 | 85 | Duke (7) | Final | W | 6 |
| 14 | 2026-01-03 | Duke (7) | 91 | 87 | Florida State (132) | Final | W | 4 |
| 15 | 2026-01-06 | Duke (9) | Louisville (28) | Scheduled – 7:00 PM | – | – | ||
| 16 | 2026-01-10 | SMU | Duke | Scheduled – 2:00 PM | – | – | ||
| 17 | 2026-01-14 | Duke | California | Scheduled – 8:00 PM | – | – | ||
| 18 | 2026-01-17 | Duke | Stanford | Scheduled – 3:00 PM | – | – | ||
| 19 | 2026-01-24 | Wake Forest | Duke | Scheduled – 5:45 PM | – | – | ||
| 20 | 2026-01-26 | Louisville | Duke | Scheduled – 7:00 PM | – | – | ||
| 21 | 2026-01-31 | Duke | Virginia Tech | Scheduled – 12:00 PM | – | – | ||
| 22 | 2026-02-03 | Boston College | Duke | Scheduled – 7:00 PM | – | – | ||
| 23 | 2026-02-07 | Duke | North Carolina | Scheduled – 6:30 PM | – | – | ||
| 24 | 2026-02-10 | Duke | Pittsburgh | Scheduled – 9:00 PM | – | – | ||
| 25 | 2026-02-14 | Clemson | Duke | Scheduled – 12:00 PM | – | – | ||
| 26 | 2026-02-16 | Syracuse | Duke | Scheduled – 7:00 PM | – | – | ||
| 27 | 2026-02-21 | Michigan | Duke | Scheduled – 6:30 PM | – | – | ||
| 28 | 2026-02-24 | Duke | Notre Dame | Scheduled – 7:00 PM | – | – | ||
| 29 | 2026-02-28 | Virginia | Duke | Scheduled – 12:00 PM | – | – | ||
| 30 | 2026-03-02 | Duke | North Carolina State | Scheduled – 7:00 PM | – | – | ||
| 31 | 2026-03-07 | North Carolina | Duke | Scheduled – 6:30 PM | – | – |