Schedule:
Please note: All rankings shown are the rankings of the teams on the date that they played one another
| Game | Date | Away Team (Rank) | Away Score | Home Score | Home Team (Rank) | Game Status | Result | Margin |
|---|---|---|---|---|---|---|---|---|
| 1 | 2018-11-06 | Duke (3) | 118 | 84 | Kentucky (26) | Final | W | 34 |
| 2 | 2018-11-11 | Army (276) | 72 | 94 | Duke (4) | Final | W | 22 |
| 3 | 2018-11-14 | Eastern Michigan (134) | 46 | 84 | Duke (2) | Final | W | 38 |
| 4 | 2018-11-19 | Duke (2) | 90 | 64 | San Diego State (122) | Final | W | 26 |
| 5 | 2018-11-20 | Auburn (17) | 72 | 78 | Duke (3) | Final | W | 6 |
| 6 | 2018-11-21 | Duke (3) | 87 | 89 | Gonzaga (19) | Final | L | -2 |
| 7 | 2018-11-27 | Indiana (45) | 69 | 90 | Duke (6) | Final | W | 21 |
| 8 | 2018-12-01 | Stetson (338) | 49 | 113 | Duke (6) | Final | W | 64 |
| 9 | 2018-12-05 | Hartford (277) | 54 | 84 | Duke (2) | Final | W | 30 |
| 10 | 2018-12-08 | Yale (134) | 58 | 91 | Duke (2) | Final | W | 33 |
| 11 | 2018-12-18 | Princeton (230) | 50 | 101 | Duke (3) | Final | W | 51 |
| 12 | 2018-12-20 | Texas Tech (6) | 58 | 69 | Duke (3) | Final | W | 11 |
| 13 | 2019-01-05 | Clemson (43) | 68 | 87 | Duke (1) | Final | W | 19 |
| 14 | 2019-01-08 | Duke (1) | 87 | 65 | Wake Forest (166) | Final | W | 22 |
| 15 | 2019-01-12 | Duke (1) | 80 | 78 | Florida State (17) | Final | W | 2 |
| 16 | 2019-01-14 | Syracuse (54) | 95 | 91 | Duke (1) | Final/OT | L | -4 |
| 17 | 2019-01-19 | Virginia (2) | 70 | 72 | Duke (1) | Final | W | 2 |
| 18 | 2019-01-22 | Duke (2) | 79 | 64 | Pittsburgh (58) | Final | W | 15 |
| 19 | 2019-01-26 | Georgia Tech (97) | 53 | 66 | Duke (2) | Final | W | 13 |
| 20 | 2019-01-28 | Duke (2) | 83 | 61 | Notre Dame (76) | Final | W | 22 |
| 21 | 2019-02-02 | St. John's (41) | 61 | 91 | Duke (1) | Final | W | 30 |
| 22 | 2019-02-05 | Boston College (108) | 55 | 80 | Duke (1) | Final | W | 25 |
| 23 | 2019-02-09 | Duke (1) | 81 | 71 | Virginia (2) | Final | W | 10 |
| 24 | 2019-02-12 | Duke (1) | 71 | 69 | Louisville (17) | Final | W | 2 |
| 25 | 2019-02-16 | North Carolina State (36) | 78 | 94 | Duke (1) | Final | W | 16 |
| 26 | 2019-02-20 | North Carolina (8) | 88 | 72 | Duke (1) | Final | L | -16 |
| 27 | 2019-02-23 | Duke (1) | 75 | 65 | Syracuse (41) | Final | W | 10 |
| 28 | 2019-02-26 | Duke (1) | 72 | 77 | Virginia Tech (17) | Final | L | -5 |
| 29 | 2019-03-02 | Miami (83) | 57 | 87 | Duke (1) | Final | W | 30 |
| 30 | 2019-03-05 | Wake Forest (155) | 70 | 71 | Duke (2) | Final | W | 1 |
| 31 | 2019-03-09 | Duke (2) | 70 | 79 | North Carolina (4) | Final | L | -9 |
| 32 | 2019-03-14 | Syracuse (35) | 72 | 84 | Duke (3) | Final | W | 12 |
| 33 | 2019-03-15 | Duke (3) | 74 | 73 | North Carolina (4) | Final | W | 1 |
| 34 | 2019-03-16 | Florida State (13) | 63 | 73 | Duke (3) | Final | W | 10 |
| 35 | 2019-03-22 | North Dakota State (193) | 62 | 85 | Duke (2) | Final | W | 23 |
| 36 | 2019-03-24 | Central Florida (30) | 76 | 77 | Duke (2) | Final | W | 1 |
| 37 | 2019-03-29 | Virginia Tech (16) | 73 | 75 | Duke (2) | Final | W | 2 |
| 38 | 2019-03-31 | Michigan State (6) | 68 | 67 | Duke (2) | Final | L | -1 |