Schedule:
Please note: All rankings shown are the rankings of the teams on the date that they played one another
| Game | Date | Away Team (Rank) | Away Score | Home Score | Home Team (Rank) | Game Status | Result | Margin |
|---|---|---|---|---|---|---|---|---|
| 1 | 2018-11-06 | Western Illinois (266) | 67 | 78 | Creighton (26) | Final | W | 11 |
| 2 | 2018-11-11 | East Tennessee State (94) | 69 | 75 | Creighton (26) | Final | W | 6 |
| 3 | 2018-11-15 | Ohio State (86) | 69 | 60 | Creighton (47) | Final | L | -9 |
| 4 | 2018-11-19 | Boise State (283) | 82 | 94 | Creighton (47) | Final | W | 12 |
| 5 | 2018-11-20 | Georgia State (114) | 68 | 93 | Creighton (113) | Final | W | 25 |
| 6 | 2018-11-21 | Clemson (51) | 82 | 87 | Creighton (113) | Final | W | 5 |
| 7 | 2018-11-28 | Montana (74) | 72 | 98 | Creighton (24) | Final | W | 26 |
| 8 | 2018-12-01 | Gonzaga (2) | 103 | 92 | Creighton (24) | Final | L | -11 |
| 9 | 2018-12-08 | Creighton (26) | 75 | 94 | Nebraska (13) | Final | L | -19 |
| 10 | 2018-12-14 | Green Bay (157) | 65 | 86 | Creighton (45) | Final | W | 21 |
| 11 | 2018-12-18 | Creighton (42) | 70 | 83 | Oklahoma (13) | Final | L | -13 |
| 12 | 2018-12-20 | Coe College | 60 | 110 | Creighton (42) | Final | W | 50 |
| 13 | 2018-12-27 | UMKC (271) | 53 | 89 | Creighton (42) | Final | W | 36 |
| 14 | 2018-12-31 | Creighton (42) | 79 | 68 | Providence (58) | Final | W | 11 |
| 15 | 2019-01-05 | Creighton (39) | 69 | 84 | Butler (50) | Final | L | -15 |
| 16 | 2019-01-09 | Marquette (23) | 106 | 104 | Creighton (44) | Final/OT | L | -2 |
| 17 | 2019-01-13 | Villanova (36) | 90 | 78 | Creighton (44) | Final | L | -12 |
| 18 | 2019-01-16 | Creighton (47) | 66 | 81 | St. John’s (36) | Final | L | -15 |
| 19 | 2019-01-21 | Creighton (47) | 91 | 87 | Georgetown (81) | Final | W | 4 |
| 20 | 2019-01-25 | Butler (51) | 61 | 75 | Creighton (62) | Final | W | 14 |
| 21 | 2019-01-30 | St. John’s (41) | 83 | 67 | Creighton (46) | Final | L | -16 |
| 22 | 2019-02-03 | Xavier (83) | 54 | 76 | Creighton (46) | Final | W | 22 |
| 23 | 2019-02-06 | Creighton (52) | 59 | 66 | Villanova (15) | Final/OT | L | -7 |
| 24 | 2019-02-09 | Creighton (52) | 58 | 63 | Seton Hall (59) | Final | L | -5 |
| 25 | 2019-02-13 | Creighton (60) | 61 | 64 | Xavier (104) | Final/OT | L | -3 |
| 26 | 2019-02-17 | Seton Hall (55) | 81 | 75 | Creighton (60) | Final | L | -6 |
| 27 | 2019-02-20 | Creighton (65) | 79 | 67 | DePaul (98) | Final | W | 12 |
| 28 | 2019-02-23 | Georgetown (74) | 69 | 82 | Creighton (65) | Final | W | 13 |
| 29 | 2019-03-03 | Creighton (58) | 66 | 60 | Marquette (11) | Final | W | 6 |
| 30 | 2019-03-06 | Providence (74) | 70 | 76 | Creighton (55) | Final/OT | W | 6 |
| 31 | 2019-03-09 | DePaul (98) | 78 | 91 | Creighton (55) | Final | W | 13 |
| 32 | 2019-03-14 | Creighton (51) | 61 | 63 | Xavier (66) | Final | L | -2 |
| 33 | 2019-03-19 | Loyola-Chicago (129) | 61 | 70 | Creighton (54) | Final | W | 9 |
| 34 | 2019-03-22 | Memphis (56) | 67 | 79 | Creighton (54) | Final | W | 12 |
| 35 | 2019-03-26 | Creighton (54) | 58 | 71 | TCU (39) | Final | L | -13 |