Schedule:
Please note: All rankings shown are the rankings of the teams on the date that they played one another
| Game | Date | Away Team (Rank) | Away Score | Home Score | Home Team (Rank) | Game Status | Result | Margin |
|---|---|---|---|---|---|---|---|---|
| 1 | 2018-11-06 | St. Francis (PA) (205) | 67 | 82 | Buffalo (68) | Final | W | 15 |
| 2 | 2018-11-09 | Buffalo (68) | 99 | 94 | West Virginia (13) | Final/OT | W | 5 |
| 3 | 2018-11-12 | Buffalo (68) | 62 | 53 | Southern Illinois (130) | Final | W | 9 |
| 4 | 2018-11-21 | Dartmouth (126) | 71 | 110 | Buffalo (46) | Final | W | 39 |
| 5 | 2018-11-24 | Marist (289) | 49 | 76 | Buffalo (46) | Final | W | 27 |
| 6 | 2018-11-29 | Buffalo (22) | 96 | 77 | Milwaukee (222) | Final | W | 19 |
| 7 | 2018-12-01 | San Francisco (29) | 81 | 85 | Buffalo (22) | Final | W | 4 |
| 8 | 2018-12-05 | LeMoyne | 55 | 89 | Buffalo (10) | Final | W | 34 |
| 9 | 2018-12-08 | Buffalo (10) | 80 | 62 | St. Bonaventure (297) | Final | W | 18 |
| 10 | 2018-12-15 | Southern Illinois (82) | 65 | 73 | Buffalo (12) | Final | W | 8 |
| 11 | 2018-12-18 | Buffalo (11) | 71 | 59 | Syracuse (63) | Final | W | 12 |
| 12 | 2018-12-21 | Buffalo (11) | 85 | 103 | Marquette (20) | Final | L | -18 |
| 13 | 2018-12-29 | Buffalo (23) | 87 | 72 | Canisius (276) | Final | W | 15 |
| 14 | 2019-01-04 | Buffalo (24) | 74 | 58 | Eastern Michigan (237) | Final | W | 16 |
| 15 | 2019-01-08 | Toledo (57) | 80 | 110 | Buffalo (24) | Final | W | 30 |
| 16 | 2019-01-12 | Miami (OH) (168) | 64 | 88 | Buffalo (24) | Final | W | 24 |
| 17 | 2019-01-15 | Buffalo (16) | 88 | 79 | Western Michigan (239) | Final | W | 9 |
| 18 | 2019-01-18 | Eastern Michigan (168) | 65 | 77 | Buffalo (16) | Final | W | 12 |
| 19 | 2019-01-22 | Buffalo (12) | 75 | 77 | Northern Illinois (163) | Final | L | -2 |
| 20 | 2019-01-25 | Buffalo (12) | 88 | 79 | Kent State (114) | Final | W | 9 |
| 21 | 2019-01-29 | Ball State (134) | 59 | 83 | Buffalo (24) | Final | W | 24 |
| 22 | 2019-02-01 | Buffalo (24) | 88 | 92 | Bowling Green (128) | Final | L | -4 |
| 23 | 2019-02-09 | Central Michigan (131) | 76 | 90 | Buffalo (29) | Final | W | 14 |
| 24 | 2019-02-12 | Buffalo (27) | 76 | 70 | Akron (140) | Final | W | 6 |
| 25 | 2019-02-15 | Buffalo (27) | 88 | 82 | Toledo (49) | Final | W | 6 |
| 26 | 2019-02-19 | Ohio (178) | 67 | 114 | Buffalo (27) | Final | W | 47 |
| 27 | 2019-02-22 | Kent State (95) | 57 | 80 | Buffalo (27) | Final | W | 23 |
| 28 | 2019-02-26 | Akron (141) | 64 | 77 | Buffalo (22) | Final | W | 13 |
| 29 | 2019-03-01 | Buffalo (22) | 77 | 69 | Miami (OH) (153) | Final | W | 8 |
| 30 | 2019-03-05 | Buffalo (19) | 82 | 79 | Ohio (162) | Final | W | 3 |
| 31 | 2019-03-08 | Bowling Green (106) | 73 | 84 | Buffalo (19) | Final | W | 11 |
| 32 | 2019-03-14 | Akron (145) | 46 | 82 | Buffalo (21) | Final | W | 36 |
| 33 | 2019-03-15 | Central Michigan (124) | 81 | 85 | Buffalo (21) | Final | W | 4 |
| 34 | 2019-03-16 | Bowling Green (119) | 73 | 87 | Buffalo (21) | Final | W | 14 |
| 35 | 2019-03-22 | Arizona State (57) | 74 | 91 | Buffalo (19) | Final | W | 17 |
| 36 | 2019-03-24 | Buffalo (19) | 58 | 78 | Texas Tech (10) | Final | L | -20 |