Schedule:
Please note: All rankings shown are the rankings of the teams on the date that they played one another
| Game | Date | Away Team (Rank) | Away Score | Home Score | Home Team (Rank) | Game Status | Result | Margin |
|---|---|---|---|---|---|---|---|---|
| 1 | 2024-11-04 | American (249) | 52 | 65 | La Salle (237) | Final | L | -13 |
| 2 | 2024-11-10 | Harvard (247) | 55 | 67 | American (158) | Final | W | 12 |
| 3 | 2024-11-12 | American (188) | 66 | 74 | Siena (56) | Final | L | -8 |
| 4 | 2024-11-15 | American (256) | 55 | 107 | North Carolina (89) | Final | L | -52 |
| 5 | 2024-11-18 | American (281) | 73 | 80 | High Point (50) | Final | L | -7 |
| 6 | 2024-11-22 | UMKC (250) | 60 | 64 | American (245) | Final | W | 4 |
| 7 | 2024-11-23 | American (249) | 73 | 56 | Puerto Rico-Bayamon | Final | W | 17 |
| 8 | 2024-11-24 | American (225) | 81 | 77 | Albany (187) | Final | W | 4 |
| 9 | 2024-12-01 | Notre Dame (MD) | 52 | 97 | American (232) | Final | W | 45 |
| 10 | 2024-12-04 | George Washington (109) | 71 | 81 | American (193) | Final (OT) | W | 10 |
| 11 | 2024-12-18 | American (210) | 57 | 84 | Saint Joseph's (108) | Final | L | -27 |
| 12 | 2024-12-22 | American (212) | 58 | 63 | Virginia (88) | Final | L | -5 |
| 13 | 2024-12-29 | UMBC (234) | 96 | 93 | American (232) | Final (2OT) | L | -3 |
| 14 | 2025-01-02 | American (266) | 58 | 81 | Navy (337) | Final | L | -23 |
| 15 | 2025-01-05 | Holy Cross (199) | 64 | 75 | American (243) | Final | W | 11 |
| 16 | 2025-01-08 | American (262) | 54 | 60 | Boston University (243) | Final | L | -6 |
| 17 | 2025-01-11 | Bucknell (269) | 58 | 68 | American (247) | Final | W | 10 |
| 18 | 2025-01-13 | American (233) | 73 | 54 | Loyola-Maryland (291) | Final | W | 19 |
| 19 | 2025-01-18 | American (232) | 74 | 65 | Holy Cross (256) | Final | W | 9 |
| 20 | 2025-01-22 | Lehigh (314) | 67 | 68 | American (230) | Final | W | 1 |
| 21 | 2025-01-25 | Colgate (242) | 77 | 81 | American (221) | Final | W | 4 |
| 22 | 2025-01-29 | American (217) | 75 | 68 | Lafayette (305) | Final | W | 7 |
| 23 | 2025-02-01 | Army (245) | 68 | 71 | American (213) | Final | W | 3 |
| 24 | 2025-02-05 | American (225) | 49 | 71 | Bucknell (239) | Final | L | -22 |
| 25 | 2025-02-08 | American (217) | 78 | 75 | Lehigh (289) | Final (OT) | W | 3 |
| 26 | 2025-02-10 | Lafayette (302) | 58 | 60 | American (217) | Final | W | 2 |
| 27 | 2025-02-15 | Loyola-Maryland (315) | 51 | 72 | American (212) | Final | W | 21 |
| 28 | 2025-02-19 | American (217) | 69 | 76 | Army (235) | Final | L | -7 |
| 29 | 2025-02-22 | Boston University (276) | 44 | 48 | American (210) | Final | W | 4 |
| 30 | 2025-02-26 | Navy (302) | 68 | 60 | American (225) | Final | L | -8 |
| 31 | 2025-03-01 | American (249) | 67 | 59 | Colgate (239) | Final | W | 8 |
| 32 | 2025-03-06 | Lafayette (297) | 69 | 71 | American (213) | Final | W | 2 |
| 33 | 2025-03-09 | Colgate (263) | 62 | 72 | American (210) | Final | W | 10 |
| 34 | 2025-03-12 | Navy (285) | 52 | 74 | American (197) | Final | W | 22 |
| 35 | 2025-03-19 | Mount St Mary's (189) | 83 | 72 | American (199) | Final | L | -11 |