Schedule:
Please note: All rankings shown are the rankings of the teams on the date that they played one another
| Game | Date | Away Team (Rank) | Away Score | Home Score | Home Team (Rank) | Game Status | Result | Margin |
|---|---|---|---|---|---|---|---|---|
| 1 | 2025-11-03 | South Carolina Upstate | California Baptist | Scheduled – 7:30 PM | – | – | ||
| 2 | 2025-11-05 | South Carolina Upstate | Fresno State | Scheduled – 6:00 PM | – | – | ||
| 3 | 2025-11-08 | Southern Virginia | South Carolina Upstate | Scheduled – 12:00 PM | – | – | ||
| 4 | 2025-11-12 | Bob Jones | South Carolina Upstate | Scheduled – 7:00 PM | – | – | ||
| 5 | 2025-11-15 | South Carolina Upstate | UNC-Wilmington | Scheduled – 12:00 AM | – | – | ||
| 6 | 2025-11-19 | Tennessee Tech | South Carolina Upstate | Scheduled – 12:00 AM | – | – | ||
| 7 | 2025-11-21 | South Carolina Upstate | West Georgia | Scheduled – 12:00 AM | – | – | ||
| 8 | 2025-11-25 | North Carolina Central | South Carolina Upstate | Scheduled – 7:00 PM | – | – | ||
| 9 | 2025-11-29 | South Carolina Upstate | Nebraska | Scheduled – 7:30 PM | – | – | ||
| 10 | 2025-12-03 | Coastal Carolina | South Carolina Upstate | Scheduled – 7:00 PM | – | – | ||
| 11 | 2025-12-06 | Western Carolina | South Carolina Upstate | Scheduled – 2:00 PM | – | – | ||
| 12 | 2025-12-13 | South Carolina Upstate | North Carolina | Scheduled – 12:00 AM | – | – | ||
| 13 | 2025-12-16 | South Carolina Upstate | South Carolina State | Scheduled – 1:00 PM | – | – | ||
| 14 | 2025-12-17 | Southern Wesleyan | South Carolina Upstate | Scheduled – 7:00 PM | – | – | ||
| 15 | 2025-12-20 | South Carolina Upstate | Youngstown State | Scheduled – 1:00 PM | – | – | ||
| 16 | 2025-12-31 | Radford | South Carolina Upstate | Scheduled – 7:00 PM | – | – | ||
| 17 | 2026-01-03 | South Carolina Upstate | Presbyterian | Scheduled – 12:00 AM | – | – | ||
| 18 | 2026-01-10 | Winthrop | South Carolina Upstate | Scheduled – 2:00 PM | – | – | ||
| 19 | 2026-01-14 | South Carolina Upstate | Charleston Southern | Scheduled – 7:00 PM | – | – | ||
| 20 | 2026-01-17 | South Carolina Upstate | High Point | Scheduled – 7:00 PM | – | – | ||
| 21 | 2026-01-21 | UNC-Asheville | South Carolina Upstate | Scheduled – 7:00 PM | – | – | ||
| 22 | 2026-01-24 | South Carolina Upstate | Gardner-Webb | Scheduled – 2:00 PM | – | – | ||
| 23 | 2026-01-29 | Longwood | South Carolina Upstate | Scheduled – 7:00 PM | – | – | ||
| 24 | 2026-02-04 | South Carolina Upstate | UNC-Asheville | Scheduled – 12:00 AM | – | – | ||
| 25 | 2026-02-07 | Charleston Southern | South Carolina Upstate | Scheduled – 2:00 PM | – | – | ||
| 26 | 2026-02-12 | High Point | South Carolina Upstate | Scheduled – 7:00 PM | – | – | ||
| 27 | 2026-02-14 | South Carolina Upstate | Longwood | Scheduled – 12:00 AM | – | – | ||
| 28 | 2026-02-19 | South Carolina Upstate | Winthrop | Scheduled – 12:00 AM | – | – | ||
| 29 | 2026-02-21 | Presbyterian | South Carolina Upstate | Scheduled – 4:30 PM | – | – | ||
| 30 | 2026-02-26 | South Carolina Upstate | Radford | Scheduled – 12:00 AM | – | – | ||
| 31 | 2026-02-28 | Gardner-Webb | South Carolina Upstate | Scheduled – 2:00 PM | – | – |