NCAA Women’s Basketball Schedule:
| Game | Date | Away Team (Rank) | Away Score | Home Score | Home Team (Rank) | Game Status | Result | Margin |
|---|---|---|---|---|---|---|---|---|
| 1 | 2021-11-10 | Radford (286) | 63 | 82 | Pittsburgh (144) | Final | W | 19 |
| 2 | 2021-11-12 | Lafayette (221) | 63 | 72 | Pittsburgh (144) | Final | W | 9 |
| 3 | 2021-11-17 | Long Island (254) | 41 | 92 | Pittsburgh (78) | Final | W | 51 |
| 4 | 2021-11-20 | Pittsburgh (78) | 69 | 64 | Duquesne (257) | Final | W | 5 |
| 5 | 2021-11-25 | Pittsburgh (59) | 46 | 57 | Texas A&M (3) | Final | L | -11 |
| 6 | 2021-11-26 | Northwestern (65) | 60 | 72 | Pittsburgh (59) | Final | W | 12 |
| 7 | 2021-11-27 | Pittsburgh (59) | 61 | 72 | South Dakota (126) | Final/OT | L | -11 |
| 8 | 2021-12-01 | Rutgers (127) | 50 | 58 | Pittsburgh (78) | Final | W | 8 |
| 9 | 2021-12-04 | Pittsburgh (78) | 64 | 54 | Ball State (144) | Final | W | 10 |
| 10 | 2021-12-07 | Coppin State (167) | 51 | 67 | Pittsburgh (56) | Final | W | 16 |
| 11 | 2021-12-10 | North Carolina State (2) | 89 | 54 | Pittsburgh (56) | Final | L | -35 |
| 12 | 2021-12-19 | Pittsburgh (63) | 59 | 85 | Notre Dame (24) | Final | L | -26 |
| 13 | 2021-12-22 | Holy Cross (173) | 56 | 67 | Pittsburgh (66) | Final | W | 11 |
| 14 | 2021-12-30 | Georgia Tech (28) | 0 | 0 | Pittsburgh (61) | Postponed | – | – |
| 15 | 2022-01-06 | Pittsburgh (64) | 39 | 81 | Louisville (6) | Final | L | -42 |
| 16 | 2022-01-11 | Georgia Tech (30) | 63 | 52 | Pittsburgh (75) | Final | L | -11 |
| 17 | 2022-01-13 | Boston College (44) | 75 | 64 | Pittsburgh (75) | Final | L | -11 |
| 18 | 2022-01-16 | Wake Forest (61) | 57 | 65 | Pittsburgh (75) | Final | W | 8 |
| 19 | 2022-01-20 | Pittsburgh (79) | 65 | 75 | Virginia Tech (25) | Final | L | -10 |
| 20 | 2022-01-23 | Notre Dame (16) | 77 | 63 | Pittsburgh (79) | Final | L | -14 |
| 21 | 2022-01-27 | Pittsburgh (84) | 78 | 73 | Clemson (131) | Final/OT | W | 5 |
| 22 | 2022-01-30 | Pittsburgh (84) | 72 | 80 | Syracuse (96) | Final | L | -8 |
| 23 | 2022-02-03 | Duke (34) | 54 | 39 | Pittsburgh (86) | Final | L | -15 |
| 24 | 2022-02-10 | Pittsburgh (89) | 54 | 64 | North Carolina (12) | Final | L | -10 |
| 25 | 2022-02-13 | Syracuse (98) | 67 | 65 | Pittsburgh (89) | Final | L | -2 |
| 26 | 2022-02-15 | Pittsburgh (98) | 57 | 69 | Boston College (51) | Final | L | -12 |
| 27 | 2022-02-17 | Pittsburgh (98) | 50 | 60 | Miami (62) | Final | L | -10 |
| 28 | 2022-02-20 | Pittsburgh (98) | 65 | 74 | Virginia (232) | Final | L | -9 |
| 29 | 2022-02-24 | Louisville (4) | 66 | 55 | Pittsburgh (108) | Final | L | -11 |
| 30 | 2022-02-27 | Florida State (67) | 57 | 52 | Pittsburgh (108) | Final | L | -5 |
| 31 | 2022-03-02 | Pittsburgh (112) | 52 | 55 | Duke (50) | Final | L | -3 |