NCAA Women’s Basketball Schedule:
| Game | Date | Away Team (Rank) | Away Score | Home Score | Home Team (Rank) | Game Status | Result | Margin |
|---|---|---|---|---|---|---|---|---|
| 1 | 2020-12-04 | Seton Hall (209) | 0 | 0 | Butler (141) | Postponed | – | – |
| 2 | 2020-12-05 | Providence (91) | 73 | 52 | Butler (141) | Final | L | -21 |
| 3 | 2020-12-06 | Creighton (349) | 88 | 41 | Butler (141) | Final | L | -47 |
| 4 | 2020-12-09 | Butler (348) | 54 | 93 | Michigan (20) | Final | L | -39 |
| 5 | 2020-12-12 | Butler (348) | 0 | 0 | Indiana (50) | Postponed | – | – |
| 6 | 2020-12-15 | Butler (348) | Connecticut (157) | 12/15 – 7:00 PM EST | – | – | ||
| 7 | 2020-12-19 | Butler (338) | Creighton (199) | Postponed | – | – | ||
| 8 | 2020-12-22 | Evansville (255) | 0 | 0 | Butler (338) | Postponed | – | – |
| 9 | 2020-12-31 | Butler (330) | 45 | 56 | Georgetown (224) | Final | L | -11 |
| 10 | 2021-01-07 | DePaul (24) | 0 | 0 | Butler (329) | 1/7 – 2:00 PM EST | – | – |
| 11 | 2021-01-07 | Butler (329) | 50 | 62 | Providence (197) | Final | L | -12 |
| 12 | 2021-01-09 | Butler (329) | 56 | 64 | St. John’s (186) | Final | L | -8 |
| 13 | 2021-01-11 | Seton Hall (107) | 79 | 64 | Butler (329) | Final | L | -15 |
| 14 | 2021-01-13 | Georgetown (184) | 40 | 58 | Butler (325) | Final | W | 18 |
| 15 | 2021-01-17 | Butler (325) | 68 | 83 | Seton Hall (126) | Final | L | -15 |
| 16 | 2021-01-19 | Butler (325) | 35 | 103 | Connecticut (5) | Final | L | -68 |
| 17 | 2021-01-21 | DePaul (30) | 80 | 66 | Butler (307) | Final | L | -14 |
| 18 | 2021-01-24 | Marquette (56) | 95 | 57 | Butler (307) | Final | L | -38 |
| 19 | 2021-01-27 | Butler (309) | 0 | 0 | Creighton (125) | 1/27 – 7:00 PM EST | – | – |
| 20 | 2021-01-31 | Villanova (39) | 90 | 53 | Butler (309) | Final | L | -37 |
| 21 | 2021-02-08 | Butler (317) | 0 | 0 | Xavier (185) | Postponed | – | – |
| 22 | 2021-02-10 | Butler (315) | 48 | 77 | Marquette (49) | Final | L | -29 |
| 23 | 2021-02-13 | St. John’s (187) | 47 | 35 | Butler (315) | Final | L | -12 |
| 24 | 2021-02-16 | Butler (318) | 74 | 98 | Villanova (46) | Final | L | -24 |
| 25 | 2021-02-22 | Xavier (182) | 61 | 73 | Butler (318) | Final | W | 12 |
| 26 | 2021-02-24 | Butler (315) | Providence (177) | 2/24 – 1:00 PM EST | – | – | ||
| 27 | 2021-02-27 | Connecticut (1) | 97 | 68 | Butler (299) | Final | L | -29 |
| 28 | 2021-03-01 | Butler (299) | 86 | 81 | DePaul (34) | Final | W | 5 |
| 29 | 2021-03-05 | Butler (269) | 61 | 63 | Providence (186) | Final | L | -2 |