Schedule:
| Game | Date | Away Team (Rank) | Away Score | Home Team (Rank) | Home Score | Game Status | Result | Margin |
|---|---|---|---|---|---|---|---|---|
| 1 | 2024-08-31 | Akron (156) | 6 | Ohio State (7) | 52 | Final | W | 46 |
| 2 | 2024-09-07 | Western Michigan (117) | 0 | Ohio State (7) | 56 | Final | W | 56 |
| 3 | 2024-09-21 | Marshall (104) | 14 | Ohio State (10) | 49 | Final | W | 35 |
| 4 | 2024-09-28 | Ohio State (4) | 38 | Michigan State (49) | 7 | Final | W | 31 |
| 5 | 2024-10-05 | Iowa (52) | 7 | Ohio State (2) | 35 | Final | W | 28 |
| 6 | 2024-10-12 | Ohio State (6) | 31 | Oregon (2) | 32 | Final | L | -1 |
| 7 | 2024-10-26 | Nebraska (41) | 17 | Ohio State (5) | 21 | Final | W | 4 |
| 8 | 2024-11-02 | Ohio State (2) | 20 | Penn State (13) | 13 | Final | W | 7 |
| 9 | 2024-11-09 | Purdue (127) | 0 | Ohio State (3) | 45 | Final | W | 45 |
| 10 | 2024-11-16 | Ohio State (2) | 31 | Northwestern (85) | 7 | Final | W | 24 |
| 11 | 2024-11-23 | Indiana (5) | 15 | Ohio State (1) | 38 | Final | W | 23 |
| 12 | 2024-11-30 | Michigan (27) | 13 | Ohio State (4) | 10 | Final | L | -3 |
| 13 | 2024-12-21 | Tennessee (9) | 17 | Ohio State (1) | 42 | Final | W | 25 |
| 14 | 2025-01-01 | Ohio State (1) | 41 | Oregon (2) | 21 | Final | W | 20 |
| 15 | 2025-01-10 | Ohio State (1) | 28 | Texas (4) | 14 | Final | W | 14 |
| 16 | 2025-01-20 | Ohio State (1) | 34 | Notre Dame (3) | 23 | Final | W | 11 |