Schedule:
Please note: All rankings shown are the rankings of the teams on the date that they played one another
| Game | Date | Away Team (Rank) | Away Score | Home Score | Home Team (Rank) | Game Status | Result | Margin |
|---|---|---|---|---|---|---|---|---|
| 1 | 2023-11-06 | UMBC (321) | 93 | 94 | Louisville (153) | Final | W | 1 |
| 2 | 2023-11-10 | Chattanooga (64) | 81 | 71 | Louisville (192) | Final | L | -10 |
| 3 | 2023-11-15 | Coppin State (360) | 41 | 61 | Louisville (164) | Final | W | 20 |
| 4 | 2023-11-19 | Texas (26) | 81 | 80 | Louisville (166) | Final | L | -1 |
| 5 | 2023-11-20 | Indiana (98) | 74 | 66 | Louisville (208) | Final | L | -8 |
| 6 | 2023-11-26 | New Mexico State (300) | 84 | 90 | Louisville (183) | Final | W | 6 |
| 7 | 2023-11-29 | Bellarmine (288) | 68 | 73 | Louisville (185) | Final | W | 5 |
| 8 | 2023-12-03 | Louisville (204) | 68 | 75 | Virginia Tech (62) | Final | L | -7 |
| 9 | 2023-12-09 | Louisville | 0 | 0 | DePaul | Scheduled – TBA | – | – |
| 10 | 2023-12-13 | Arkansas State | 0 | 0 | Louisville | Scheduled – 08:00PM ET | – | – |
| 11 | 2023-12-17 | Pepperdine | 0 | 0 | Louisville | Scheduled – 02:00PM ET | – | – |
| 12 | 2023-12-21 | Kentucky | 0 | 0 | Louisville | Scheduled – 06:00PM ET | – | – |
| 13 | 2024-01-03 | Louisville | 0 | 0 | Virginia | Scheduled – 07:00PM ET | – | – |
| 14 | 2024-01-06 | Pittsburgh | 0 | 0 | Louisville | Scheduled – 12:00PM ET | – | – |
| 15 | 2024-01-10 | Louisville | 0 | 0 | Miami | Scheduled – 07:00PM ET | – | – |
| 16 | 2024-01-13 | North Carolina State | 0 | 0 | Louisville | Scheduled – 12:00PM ET | – | – |
| 17 | 2024-01-17 | Louisville | 0 | 0 | North Carolina | Scheduled – 09:00PM ET | – | – |
| 18 | 2024-01-20 | Louisville | 0 | 0 | Wake Forest | Scheduled – TBA | – | – |
| 19 | 2024-01-23 | Duke | 0 | 0 | Louisville | Scheduled – 07:00PM ET | – | – |
| 20 | 2024-01-27 | Virginia | 0 | 0 | Louisville | Scheduled – 12:00PM ET | – | – |
| 21 | 2024-01-30 | Louisville | 0 | 0 | Clemson | Scheduled – 09:00PM ET | – | – |
| 22 | 2024-02-03 | Florida State | 0 | 0 | Louisville | Scheduled – 08:00PM ET | – | – |
| 23 | 2024-02-07 | Louisville | 0 | 0 | Syracuse | Scheduled – 07:00PM ET | – | – |
| 24 | 2024-02-10 | Georgia Tech | 0 | 0 | Louisville | Scheduled – 06:30PM ET | – | – |
| 25 | 2024-02-13 | Louisville | 0 | 0 | Boston College | Scheduled – 09:00PM ET | – | – |
| 26 | 2024-02-17 | Louisville | 0 | 0 | Pittsburgh | Scheduled – 06:30PM ET | – | – |
| 27 | 2024-02-21 | Notre Dame | 0 | 0 | Louisville | Scheduled – 07:00PM ET | – | – |
| 28 | 2024-02-28 | Louisville | 0 | 0 | Duke | Scheduled – 07:00PM ET | – | – |
| 29 | 2024-03-02 | Syracuse | 0 | 0 | Louisville | Scheduled – 08:00PM ET | – | – |
| 30 | 2024-03-05 | Virginia Tech | 0 | 0 | Louisville | Scheduled – 07:00PM ET | – | – |
| 31 | 2024-03-09 | Boston College | 0 | 0 | Louisville | Scheduled – 05:30PM ET | – | – |