Schedule:
Please note: All rankings shown are the rankings of the teams on the date that they played one another
| Game | Date | Away Team (Rank) | Away Score | Home Score | Home Team (Rank) | Game Status | Result | Margin |
|---|---|---|---|---|---|---|---|---|
| 1 | 2022-11-08 | South Carolina State (350) | 77 | 80 | South Carolina (197) | Final | L | -3 |
| 2 | 2022-11-12 | South Carolina State (350) | 61 | 80 | Tennessee State (266) | Final | L | -19 |
| 3 | 2022-11-14 | South Carolina State (350) | 71 | 96 | Duquesne (94) | Final | L | -25 |
| 4 | 2022-11-17 | South Carolina State (350) | 63 | 106 | Kentucky (33) | Final | L | -43 |
| 5 | 2022-11-19 | South Carolina State (350) | 66 | 72 | North Florida (247) | Final | L | -6 |
| 6 | 2022-11-23 | South Carolina State (350) | 74 | 105 | Wake Forest (59) | Final | L | -31 |
| 7 | 2022-11-26 | South Carolina State (350) | 64 | 90 | Western Kentucky (167) | Final | L | -26 |
| 8 | 2022-11-29 | South Carolina State (350) | 73 | 68 | East Carolina (185) | Final | W | 5 |
| 9 | 2022-12-03 | South Carolina State (350) | 76 | 88 | Furman (105) | Final | L | -12 |
| 10 | 2022-12-06 | South Carolina State (350) | 67 | 81 | Winthrop (257) | Final | L | -14 |
| 11 | 2022-12-10 | South Carolina State (350) | 84 | 89 | South Carolina Upstate (253) | Final | L | -5 |
| 12 | 2022-12-13 | UNC-Asheville (130) | 94 | 84 | South Carolina State (350) | Final | L | -10 |
| 13 | 2022-12-17 | Samford (162) | 61 | 62 | South Carolina State (350) | Final | W | 1 |
| 14 | 2022-12-20 | South Carolina State (350) | 77 | 104 | Longwood (180) | Final | L | -27 |
| 15 | 2022-12-27 | South Carolina State (350) | 71 | 110 | Texas Tech (52) | Final | L | -39 |
| 16 | 2022-12-30 | St. Andrews | 58 | 111 | South Carolina State (350) | Final | W | 53 |
| 17 | 2023-01-07 | South Carolina State (350) | 73 | 85 | Coppin State (346) | Final | L | -12 |
| 18 | 2023-01-09 | South Carolina State (350) | 85 | 90 | Morgan State (291) | Final | L | -5 |
| 19 | 2023-01-14 | South Carolina State (350) | 67 | 71 | North Carolina Central (219) | Final | L | -4 |
| 20 | 2023-01-21 | Maryland-Eastern Shore (208) | 76 | 70 | South Carolina State (350) | Final | L | -6 |
| 21 | 2023-01-23 | Delaware State (356) | 88 | 85 | South Carolina State (350) | Final (OT) | L | -3 |
| 22 | 2023-01-28 | South Carolina State (350) | 68 | 82 | Norfolk State (143) | Final | L | -14 |
| 23 | 2023-01-30 | South Carolina State (350) | 74 | 100 | Howard (207) | Final | L | -26 |
| 24 | 2023-02-11 | Coppin State (346) | 84 | 94 | South Carolina State (350) | Final | W | 10 |
| 25 | 2023-02-13 | Morgan State (291) | 62 | 74 | South Carolina State (350) | Final | W | 12 |
| 26 | 2023-02-18 | South Carolina State (350) | 62 | 78 | Maryland-Eastern Shore (208) | Final | L | -16 |
| 27 | 2023-02-20 | South Carolina State (350) | 68 | 69 | Delaware State (356) | Final | L | -1 |
| 28 | 2023-02-25 | Norfolk State (152) | 88 | 76 | South Carolina State (352) | Final | L | -12 |
| 29 | 2023-02-27 | Howard (221) | 82 | 78 | South Carolina State (352) | Final | L | -4 |
| 30 | 2023-03-02 | North Carolina Central (180) | 71 | 64 | South Carolina State (352) | Final | L | -7 |
| 31 | 2023-03-08 | South Carolina State (353) | 55 | 91 | Howard (204) | Final | L | -36 |