Schedule:
Please note: All rankings shown are the rankings of the teams on the date that they played one another
| Game | Date | Away Team (Rank) | Away Score | Home Score | Home Team (Rank) | Game Status | Result | Margin |
|---|---|---|---|---|---|---|---|---|
| 1 | 2022-11-07 | Eastern Washington (110) | 72 | 84 | Santa Clara (56) | Final | W | 12 |
| 2 | 2022-11-10 | Georgia Southern (221) | 62 | 78 | Santa Clara (56) | Final | W | 16 |
| 3 | 2022-11-14 | Santa Clara (56) | 74 | 96 | Utah State (37) | Final | L | -22 |
| 4 | 2022-11-18 | Santa Clara (56) | 69 | 61 | DePaul (159) | Final | W | 8 |
| 5 | 2022-11-20 | Santa Clara (56) | 50 | 57 | Central Florida (71) | Final | L | -7 |
| 6 | 2022-11-23 | Menlo | 51 | 64 | Santa Clara (56) | Final | W | 13 |
| 7 | 2022-11-27 | Iona (84) | 76 | 86 | Santa Clara (56) | Final | W | 10 |
| 8 | 2022-11-30 | Santa Clara (56) | 89 | 85 | Wyoming (203) | Final (OT) | W | 4 |
| 9 | 2022-12-03 | Sacramento State (256) | 65 | 72 | Santa Clara (56) | Final | W | 7 |
| 10 | 2022-12-07 | New Mexico State (218) | 65 | 66 | Santa Clara (56) | Final | W | 1 |
| 11 | 2022-12-10 | San Jose State (102) | 75 | 64 | Santa Clara (56) | Final | L | -11 |
| 12 | 2022-12-13 | Portland State (244) | 75 | 78 | Santa Clara (56) | Final | W | 3 |
| 13 | 2022-12-15 | UC-Irvine (95) | 74 | 86 | Santa Clara (56) | Final | W | 12 |
| 14 | 2022-12-22 | Boise State (30) | 58 | 73 | Santa Clara (56) | Final | W | 15 |
| 15 | 2022-12-29 | San Francisco (111) | 67 | 79 | Santa Clara (56) | Final | W | 12 |
| 16 | 2022-12-31 | Saint Mary's (12) | 67 | 64 | Santa Clara (56) | Final | L | -3 |
| 17 | 2023-01-05 | Santa Clara (56) | 89 | 79 | Pepperdine (236) | Final | W | 10 |
| 18 | 2023-01-07 | Gonzaga (8) | 81 | 76 | Santa Clara (56) | Final | L | -5 |
| 19 | 2023-01-14 | Santa Clara (56) | 92 | 81 | Pacific (228) | Final | W | 11 |
| 20 | 2023-01-19 | BYU (107) | 76 | 83 | Santa Clara (56) | Final | W | 7 |
| 21 | 2023-01-21 | Santa Clara (56) | 58 | 77 | Saint Mary's (12) | Final | L | -19 |
| 22 | 2023-01-28 | Pacific (228) | 95 | 89 | Santa Clara (56) | Final | L | -6 |
| 23 | 2023-02-02 | Santa Clara (56) | 70 | 88 | Gonzaga (8) | Final | L | -18 |
| 24 | 2023-02-04 | Santa Clara (56) | 84 | 70 | San Francisco (111) | Final | W | 14 |
| 25 | 2023-02-09 | San Diego (230) | 75 | 80 | Santa Clara (56) | Final | W | 5 |
| 26 | 2023-02-11 | Loyola Marymount (97) | 69 | 71 | Santa Clara (56) | Final | W | 2 |
| 27 | 2023-02-16 | Santa Clara (56) | 81 | 74 | BYU (107) | Final | W | 7 |
| 28 | 2023-02-18 | Santa Clara (56) | 103 | 84 | Portland (177) | Final | W | 19 |
| 29 | 2023-02-23 | Pepperdine (237) | 82 | 91 | Santa Clara (57) | Final | W | 9 |
| 30 | 2023-02-25 | Santa Clara (58) | 81 | 63 | San Diego (234) | Final | W | 18 |
| 31 | 2023-03-05 | San Francisco (103) | 93 | 87 | Santa Clara (67) | Final | L | -6 |
| 32 | 2023-03-15 | Sam Houston State | 58 | 56 | Santa Clara | Final | L | -2 |