Schedule:
Please note: All rankings shown are the rankings of the teams on the date that they played one another
| Game | Date | Away Team (Rank) | Away Score | Home Score | Home Team (Rank) | Game Status | Result | Margin |
|---|---|---|---|---|---|---|---|---|
| 1 | 2022-11-07 | Murray State (179) | 68 | 91 | Saint Louis (80) | Final | W | 23 |
| 2 | 2022-11-12 | Evansville (344) | 65 | 83 | Saint Louis (80) | Final | W | 18 |
| 3 | 2022-11-15 | Memphis (36) | 84 | 90 | Saint Louis (80) | Final | W | 6 |
| 4 | 2022-11-19 | Saint Louis (80) | 67 | 95 | Maryland (28) | Final | L | -28 |
| 5 | 2022-11-20 | Providence (31) | 73 | 76 | Saint Louis (80) | Final | W | 3 |
| 6 | 2022-11-23 | Paul Quinn | 53 | 96 | Saint Louis (80) | Final | W | 43 |
| 7 | 2022-11-27 | Saint Louis (80) | 60 | 65 | Auburn (32) | Final | L | -5 |
| 8 | 2022-11-30 | Tennessee State (266) | 63 | 80 | Saint Louis (80) | Final | W | 17 |
| 9 | 2022-12-03 | Southern Illinois (113) | 72 | 85 | Saint Louis (80) | Final | W | 13 |
| 10 | 2022-12-06 | Saint Louis (80) | 62 | 84 | Iona (84) | Final | L | -22 |
| 11 | 2022-12-10 | Boise State (30) | 57 | 52 | Saint Louis (80) | Final | L | -5 |
| 12 | 2022-12-17 | Drake (64) | 75 | 83 | Saint Louis (80) | Final | W | 8 |
| 13 | 2022-12-21 | SIU-Edwardsville (241) | 69 | 67 | Saint Louis (80) | Final | L | -2 |
| 14 | 2022-12-31 | Saint Louis (80) | 83 | 78 | Saint Joseph's (170) | Final | W | 5 |
| 15 | 2023-01-04 | Saint Louis (80) | 81 | 90 | Massachusetts (155) | Final | L | -9 |
| 16 | 2023-01-07 | St. Bonaventure (171) | 55 | 78 | Saint Louis (80) | Final | W | 23 |
| 17 | 2023-01-11 | George Mason (131) | 62 | 63 | Saint Louis (80) | Final | W | 1 |
| 18 | 2023-01-14 | Saint Louis (80) | 81 | 74 | George Washington (191) | Final | W | 7 |
| 19 | 2023-01-18 | Saint Louis (80) | 76 | 59 | Loyola-Chicago (245) | Final | W | 17 |
| 20 | 2023-01-21 | La Salle (182) | 71 | 84 | Saint Louis (80) | Final | W | 13 |
| 21 | 2023-01-27 | Saint Louis (80) | 74 | 70 | Davidson (153) | Final | W | 4 |
| 22 | 2023-01-31 | Saint Louis (80) | 65 | 75 | Fordham (86) | Final | L | -10 |
| 23 | 2023-02-03 | Virginia Commonwealth (57) | 73 | 65 | Saint Louis (80) | Final | L | -8 |
| 24 | 2023-02-07 | Rhode Island (234) | 71 | 76 | Saint Louis (80) | Final | W | 5 |
| 25 | 2023-02-10 | Saint Louis (80) | 56 | 70 | Dayton (81) | Final | L | -14 |
| 26 | 2023-02-15 | Davidson (153) | 65 | 78 | Saint Louis (80) | Final | W | 13 |
| 27 | 2023-02-18 | Duquesne (94) | 85 | 90 | Saint Louis (80) | Final | W | 5 |
| 28 | 2023-02-21 | Saint Louis (80) | 78 | 81 | Richmond (157) | Final | L | -3 |
| 29 | 2023-02-25 | Loyola-Chicago (247) | 62 | 81 | Saint Louis (85) | Final | W | 19 |
| 30 | 2023-02-28 | Saint Louis (91) | 67 | 79 | Virginia Commonwealth (49) | Final | L | -12 |
| 31 | 2023-03-03 | Dayton (77) | 61 | 65 | Saint Louis (90) | Final | W | 4 |
| 32 | 2023-03-09 | George Mason (117) | 54 | 82 | Saint Louis (80) | Final | W | 28 |
| 33 | 2023-03-11 | Saint Louis (83) | 78 | 90 | Virginia Commonwealth (43) | Final | L | -12 |