Schedule:
Please note: All rankings shown are the rankings of the teams on the date that they played one another
| Game | Date | Away Team (Rank) | Away Score | Home Score | Home Team (Rank) | Game Status | Result | Margin |
|---|---|---|---|---|---|---|---|---|
| 1 | 2022-11-07 | Bethune-Cookman (354) | 58 | 89 | Iowa (43) | Final | W | 31 |
| 2 | 2022-11-11 | North Carolina A&T (280) | 71 | 112 | Iowa (43) | Final | W | 41 |
| 3 | 2022-11-16 | Iowa (43) | 83 | 67 | Seton Hall (73) | Final | W | 16 |
| 4 | 2022-11-21 | Nebraska-Omaha (313) | 64 | 100 | Iowa (43) | Final | W | 36 |
| 5 | 2022-11-25 | Iowa (43) | 74 | 71 | Clemson (63) | Final | W | 3 |
| 6 | 2022-11-26 | Iowa (43) | 66 | 79 | TCU (23) | Final | L | -13 |
| 7 | 2022-11-29 | Georgia Tech (168) | 65 | 81 | Iowa (43) | Final | W | 16 |
| 8 | 2022-12-06 | Iowa (43) | 62 | 74 | Duke (25) | Final | L | -12 |
| 9 | 2022-12-08 | Iowa State (20) | 56 | 75 | Iowa (43) | Final | W | 19 |
| 10 | 2022-12-11 | Wisconsin (53) | 78 | 75 | Iowa (43) | Final | L | -3 |
| 11 | 2022-12-17 | Southeast Missouri State (250) | 75 | 106 | Iowa (43) | Final | W | 31 |
| 12 | 2022-12-21 | Eastern Illinois (341) | 92 | 83 | Iowa (43) | Final | L | -9 |
| 13 | 2022-12-29 | Iowa (43) | 50 | 66 | Nebraska (83) | Final | L | -16 |
| 14 | 2023-01-01 | Iowa (43) | 79 | 83 | Penn State (54) | Final | L | -4 |
| 15 | 2023-01-05 | Indiana (19) | 89 | 91 | Iowa (43) | Final | W | 2 |
| 16 | 2023-01-08 | Iowa (43) | 76 | 65 | Rutgers (40) | Final | W | 11 |
| 17 | 2023-01-12 | Michigan (55) | 84 | 93 | Iowa (43) | Final | W | 9 |
| 18 | 2023-01-15 | Maryland (28) | 67 | 81 | Iowa (43) | Final | W | 14 |
| 19 | 2023-01-21 | Iowa (43) | 77 | 93 | Ohio State (92) | Final | L | -16 |
| 20 | 2023-01-26 | Iowa (43) | 61 | 63 | Michigan State (41) | Final | L | -2 |
| 21 | 2023-01-29 | Rutgers (40) | 82 | 93 | Iowa (43) | Final | W | 11 |
| 22 | 2023-01-31 | Northwestern (24) | 70 | 86 | Iowa (43) | Final | W | 16 |
| 23 | 2023-02-04 | Illinois (34) | 79 | 81 | Iowa (43) | Final | W | 2 |
| 24 | 2023-02-09 | Iowa (43) | 73 | 87 | Purdue (4) | Final | L | -14 |
| 25 | 2023-02-12 | Iowa (43) | 68 | 56 | Minnesota (214) | Final | W | 12 |
| 26 | 2023-02-16 | Ohio State (92) | 75 | 92 | Iowa (43) | Final | W | 17 |
| 27 | 2023-02-19 | Iowa (43) | 60 | 80 | Northwestern (24) | Final | L | -20 |
| 28 | 2023-02-22 | Iowa (46) | 52 | 64 | Wisconsin (52) | Final | L | -12 |
| 29 | 2023-02-25 | Michigan State (41) | 106 | 112 | Iowa (45) | Final | W | 6 |
| 30 | 2023-02-28 | Iowa (41) | 90 | 68 | Indiana (21) | Final | W | 22 |
| 31 | 2023-03-05 | Nebraska (75) | 81 | 77 | Iowa (41) | Final | L | -4 |
| 32 | 2023-03-09 | Ohio State (72) | 73 | 69 | Iowa (43) | Final | L | -4 |
| 33 | 2023-03-16 | Auburn | 83 | 75 | Iowa | Final | L | -8 |