Schedule:
Please note: All rankings shown are the rankings of the teams on the date that they played one another
| Game | Date | Away Team (Rank) | Away Score | Home Score | Home Team (Rank) | Game Status | Result | Margin |
|---|---|---|---|---|---|---|---|---|
| 1 | 2022-11-07 | Siena (166) | 75 | 68 | Holy Cross (327) | Final | L | -7 |
| 2 | 2022-11-10 | Dean | 71 | 85 | Holy Cross (327) | Final | W | 14 |
| 3 | 2022-11-14 | Holy Cross (327) | 65 | 94 | Creighton (21) | Final | L | -29 |
| 4 | 2022-11-19 | Stonehill (297) | 81 | 79 | Holy Cross (327) | Final | L | -2 |
| 5 | 2022-11-21 | Holy Cross (327) | 53 | 67 | Fordham (86) | Final | L | -14 |
| 6 | 2022-11-22 | Holy Cross (327) | 66 | 89 | Illinois-Chicago (271) | Final | L | -23 |
| 7 | 2022-11-27 | Colby-Sawyer | 61 | 95 | Holy Cross (327) | Final | W | 34 |
| 8 | 2022-11-30 | Harvard (183) | 72 | 38 | Holy Cross (327) | Final | L | -34 |
| 9 | 2022-12-03 | Central Connecticut State (330) | 57 | 63 | Holy Cross (327) | Final | W | 6 |
| 10 | 2022-12-07 | Quinnipiac (150) | 75 | 71 | Holy Cross (327) | Final | L | -4 |
| 11 | 2022-12-10 | Holy Cross (327) | 58 | 59 | Northeastern (278) | Final | L | -1 |
| 12 | 2022-12-19 | Holy Cross (327) | 60 | 78 | New Hampshire (260) | Final | L | -18 |
| 13 | 2022-12-22 | Holy Cross (327) | 62 | 66 | Sacred Heart (311) | Final | L | -4 |
| 14 | 2022-12-30 | Bucknell (305) | 58 | 60 | Holy Cross (327) | Final | W | 2 |
| 15 | 2023-01-02 | Holy Cross (327) | 74 | 63 | Navy (205) | Final | W | 11 |
| 16 | 2023-01-05 | American (248) | 73 | 68 | Holy Cross (327) | Final | L | -5 |
| 17 | 2023-01-08 | Loyola-Maryland (328) | 55 | 63 | Holy Cross (327) | Final | W | 8 |
| 18 | 2023-01-11 | Holy Cross (327) | 58 | 76 | Lehigh (243) | Final | L | -18 |
| 19 | 2023-01-14 | Holy Cross (327) | 48 | 62 | Lafayette (298) | Final | L | -14 |
| 20 | 2023-01-18 | Colgate (124) | 77 | 71 | Holy Cross (327) | Final | L | -6 |
| 21 | 2023-01-21 | Holy Cross (327) | 80 | 73 | Bucknell (305) | Final | W | 7 |
| 22 | 2023-01-25 | Lehigh (243) | 74 | 68 | Holy Cross (327) | Final | L | -6 |
| 23 | 2023-01-28 | Holy Cross (327) | 55 | 66 | Army (258) | Final | L | -11 |
| 24 | 2023-02-01 | Holy Cross (327) | 82 | 70 | Boston University (274) | Final | W | 12 |
| 25 | 2023-02-04 | Navy (205) | 86 | 68 | Holy Cross (327) | Final | L | -18 |
| 26 | 2023-02-06 | Lafayette (298) | 72 | 58 | Holy Cross (327) | Final | L | -14 |
| 27 | 2023-02-11 | Holy Cross (327) | 74 | 66 | American (248) | Final | W | 8 |
| 28 | 2023-02-15 | Boston University (274) | 69 | 71 | Holy Cross (327) | Final | W | 2 |
| 29 | 2023-02-18 | Holy Cross (327) | 73 | 96 | Colgate (124) | Final | L | -23 |
| 30 | 2023-02-22 | Holy Cross (330) | 68 | 90 | Loyola-Maryland (322) | Final | L | -22 |
| 31 | 2023-02-25 | Army (261) | 80 | 65 | Holy Cross (335) | Final | L | -15 |
| 32 | 2023-02-28 | Holy Cross (339) | 69 | 73 | Loyola-Maryland (312) | Final | L | -4 |