Schedule:
Please note: All rankings shown are the rankings of the teams on the date that they played one another
| Game | Date | Away Team (Rank) | Away Score | Home Score | Home Team (Rank) | Game Status | Result | Margin |
|---|---|---|---|---|---|---|---|---|
| 1 | 2020-11-25 | UTRGV (262) | 55 | 91 | Texas (52) | Final | L | -36 |
| 2 | 2020-11-28 | UTSA (232) | 64 | 81 | UTRGV (262) | Final | W | 17 |
| 3 | 2020-12-02 | Texas A&M-Corpus Christi (304) | 59 | 62 | UTRGV (239) | Final | W | 3 |
| 4 | 2020-12-04 | Lady of the Lake | 68 | 91 | UTRGV (239) | Final | W | 23 |
| 5 | 2020-12-06 | UTRGV (239) | 68 | 81 | Texas A&M (58) | Final | L | -13 |
| 6 | 2020-12-10 | UTRGV (220) | 68 | 64 | Texas A&M-Corpus Christi (336) | Final | W | 4 |
| 7 | 2020-12-14 | UTRGV (220) | Incarnate Word (330) | Scheduled – 08:00PM ET | – | – | ||
| 8 | 2020-12-14 | Texas A&M-International | 51 | 89 | UTRGV (220) | Final | W | 38 |
| 9 | 2020-12-21 | Sam Houston State (219) | 69 | 66 | UTRGV (211) | Final | L | -3 |
| 10 | 2021-01-05 | Dallas Christian | 0 | 0 | UTRGV (205) | Scheduled – 07:00PM ET | – | – |
| 11 | 2021-01-07 | Saint Mary’s (TX) | 67 | 96 | UTRGV (205) | Final | W | 29 |
| 12 | 2021-01-08 | UTRGV (205) | Chicago State (355) | Scheduled – TBA | – | – | ||
| 13 | 2021-01-09 | UTRGV (205) | Chicago State (355) | Scheduled – TBA | – | – | ||
| 14 | 2021-01-15 | Dixie State (211) | 49 | 82 | UTRGV (184) | Final | W | 33 |
| 15 | 2021-01-16 | Dixie State (211) | 65 | 72 | UTRGV (184) | Final | W | 7 |
| 16 | 2021-01-22 | UTRGV | 0 | 0 | New Mexico State | Scheduled – 09:00PM ET | – | – |
| 17 | 2021-01-23 | UTRGV | 0 | 0 | New Mexico State | Scheduled – 09:00PM ET | – | – |
| 18 | 2021-02-05 | Grand Canyon (106) | 0 | 0 | UTRGV (170) | Scheduled – 08:00PM ET | – | – |
| 19 | 2021-02-06 | Grand Canyon | 0 | 0 | UTRGV | Scheduled – 08:00PM ET | – | – |
| 20 | 2021-02-06 | UTRGV (170) | 75 | 77 | Texas Southern (248) | Final | L | -2 |
| 21 | 2021-02-12 | UTRGV (186) | 0 | 0 | California Baptist (237) | Scheduled – 09:00PM ET | – | – |
| 22 | 2021-02-13 | UTRGV (186) | 0 | 0 | California Baptist (237) | Scheduled – 09:00PM ET | – | – |
| 23 | 2021-02-19 | Seattle | 0 | 0 | UTRGV | Scheduled – 08:00PM ET | – | – |
| 24 | 2021-02-20 | Seattle | 0 | 0 | UTRGV | Scheduled – 08:00PM ET | – | – |
| 25 | 2021-02-21 | Dallas Christian | 51 | 116 | UTRGV (170) | Final | W | 65 |
| 26 | 2021-02-26 | UTRGV (170) | 74 | 78 | Utah Valley (237) | Final | L | -4 |
| 27 | 2021-02-27 | UTRGV (170) | 64 | 73 | Utah Valley (237) | Final | L | -9 |
| 28 | 2021-03-02 | UTRGV (190) | 51 | 69 | New Mexico State (271) | Final | L | -18 |
| 29 | 2021-03-05 | Tarleton State (258) | 65 | 47 | UTRGV (190) | Final | L | -18 |
| 30 | 2021-03-06 | Tarleton State (258) | 69 | 58 | UTRGV (190) | Final | L | -11 |
| 31 | 2021-03-11 | UTRGV (263) | 61 | 77 | New Mexico State (210) | Final | L | -16 |